The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.
Notable, our Alpha technology is a highly flexible, homogenous, no-wash assay ideal for the measurement of protein interactions and complexes as large as 200 nm in size. A bead-based proximity assay, Alpha technology offers the possibility to assay many biological targets including enzymes, receptor-ligand interactions, low-affinity interactions, second messenger levels, DNA, RNA, proteins, peptides, sugars and small molecules.
The full measurement capabilities of our protein-protein interaction analysis technologies include:
- Transient and stable interactions
- Low-to-high affinity interactions (pM to mM affinity)
- Full-length protein-protein binding
- Peptide-protein
- Receptor dimerization
- Protein-small molecule
- Protein complex interactions
